Genome Editing / CRISPR-Cas field

Technologies curated under the Genome Editing / CRISPR-Cas field in TechTree.

Modern

• NHEJ and HDR DNA Repair Editing (dna_repair_nhej_hdr) — 1953 / decade
• Genetic Engineering (genetic_engineering) — 1977 / decade
• Protein Engineering (protein_engineering) — 1977 / decade
• Systems Biology (systems_biology) — 1977 / decade
• Viral Vectors (viral_vectors) — 1977 / decade
• DNA Synthesis & Oligonucleotides (dna_synthesis_oligonucleotides) — 1983 / exact
• CRISPR Adaptive Immunity (crispr_adaptive_immunity) — 1987 / exact
• Zinc-Finger Nucleases (zinc_finger_nucleases) — 1996 / exact
• RNA Interference (rna_interference) — 1998 / exact
• Synthetic Biology (synthetic_biology) — 2000 / decade
• TALENs (talens) — 2011 / exact
• PAM Recognition Constraint (pam_recognition_constraint) — 2012 / exact
• Programmable Cas9 Nuclease (cas9_programmable_nuclease) — 2012 / exact
• Single-Guide RNA Design (single_guide_rna_design) — 2012 / exact
• CRISPR Off-Target Profiling (crispr_off_target_profiling) — 2013 / decade
• CRISPR-Cas9 Genome Editing (crispr_gene_editing) — 2013 / exact
• CRISPRi and CRISPRa (crispri_crispra) — 2013 / exact
• Pooled CRISPR Screens (pooled_crispr_screens) — 2014 / exact
• Cas12 and Cas13 Editing Platforms (cas12_cas13_editing_platforms) — 2015 / decade
• CRISPR Delivery: AAV, LNP, and RNP (crispr_delivery_aav_lnp_rnp) — 2015 / decade
• Engineered PAM Specificity Variants (pam_specificity_engineering) — 2015 / exact
• Base Editing (base_editing) — 2016 / exact
• Ex Vivo CRISPR Cell Therapy (ex_vivo_crispr_cell_therapy) — 2016 / decade
• Prime Editing (prime_editing) — 2019 / exact
• Casgevy / Exa-cel (casgevy_exa_cel) — 2023 / exact

Future

• Clinical Prime Editing (clinical_prime_editing) — 2030 / decade
• In Vivo CRISPR Therapeutics (in_vivo_crispr_therapeutics) — 2030 / decade
• Tissue-Targeted Editor Delivery (tissue_targeted_editor_delivery) — 2030 / decade