Gene Therapy (Early)

Experimental techniques to treat or cure diseases by modifying an individual's genes.

Core metadata

ID: gene_therapy_early
Era: Modern
First known date: 1990 (exact)
Region: Bethesda, Maryland, United States
Review status: source_checked
Maturity: N/A

Prerequisites

Dependents

None.

Fields

None.

Node sources

Results From First Human Gene Therapy Clinical Trial (National Human Genome Research Institute, 1995, official_agency) • Supports: node
Locator: NHGRI states that NIH researchers initiated gene therapy for the first patient on September 14, 1990.

Prerequisite edge evidence

Edge/source evidence summary:

Prerequisite edges: 4
Average edge confidence: 68%
Prerequisite sources: 3
expert_inference: 4

Prerequisite	Type	Confidence	Evidence level	Note	Sources
DNA Sequencing (dna_sequencing)	enabling	68%	expert_inference	DNA Sequencing provides a capability that enables this technology without being the only possible path.	DNA sequencing with chain-terminating inhibitors (Proceedings of the National Academy of Sciences / PubMed, 1977, primary_paper) • Supports: edge
Molecular Biology (molecular_biology)	enabling	68%	expert_inference	Molecular Biology provides a capability that enables this technology without being the only possible path.	Molecular Biology of the Cell (NCBI Bookshelf, 2002, textbook) • Supports: edge
DNA Structure (dna_structure)	enabling	68%	expert_inference	DNA Structure provides a capability that enables this technology without being the only possible path.	Molecular Structure of Nucleic Acids (Nature, 1953, primary_paper) • Supports: edge
Advanced Immunology (immunology_advanced)	enabling	68%	expert_inference	Advanced Immunology provides a capability that enables this technology without being the only possible path.	No sources recorded.

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