Double-Blind Clinical Trials

Clinical trial design in which participants and investigators are masked to treatment assignment to reduce bias.

Core metadata

ID: double_blind_clinical_trials
Era: Modern
First known date: 1950 (decade)
Region: Europe, North America, and global clinical research
Review status: source_checked
Maturity: established

Prerequisites

Dependents

Phase I-III Clinical Trials (phase_i_iii_clinical_trials)

Fields

Pharmaceuticals & Drug Development

Field lanes

Pharmaceuticals & Drug Development: Clinical Development & Regulation

Node sources

ClinicalTrials.gov Glossary (ClinicalTrials.gov, 2026, official_agency) • Supports: node, maturity

Prerequisite edge evidence

Edge/source evidence summary:

Prerequisite edges: 3
Average edge confidence: 68%
Prerequisite sources: 3
expert_inference: 3

Prerequisite	Type	Confidence	Evidence level	Note	Sources
Randomized Controlled Trials (randomized_controlled_trials)	enabling	68%	expert_inference	Randomized Controlled Trials provides a capability that enables this technology without being the only possible path.	ClinicalTrials.gov Glossary (ClinicalTrials.gov, 2026, official_agency) • Supports: node, maturity, edge
Experimental Controls (experimental_controls)	enabling	68%	expert_inference	Experimental Controls provides a capability that enables this technology without being the only possible path.	ClinicalTrials.gov Glossary (ClinicalTrials.gov, 2026, official_agency) • Supports: node, maturity, edge
Public Health Statistics (public_health_statistics)	enabling	68%	expert_inference	Public Health Statistics provides a capability that enables this technology without being the only possible path.	ClinicalTrials.gov Glossary (ClinicalTrials.gov, 2026, official_agency) • Supports: node, maturity, edge

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